HEDDAONBROADWAY-COMMON DISEASE AND ITS REMEDIES

MEDICINE FOR MACROLIDE ANTIBIOTICS

The medicine which destroys the bacteria or slows down their growth is Macrolide Antibiotics. Mostly this medicine is given for respiratory tract infection. Macrolides are derived from Streptomyces species. They have a common macrolytic lactone ring to which one or more sugars are attached. They are different from one another in their chemical substitutions on structures of various carbon atoms and the amino and neutral sugars. Macrolide antibiotics are noted for their intracellular accumulation and activity against intracellular pathogens such as Mycoplasma pneumoniae, Chlamydia pneumoniae and Legionella spp. One of the common medicines given for the treatment is Erythromycin. The brand name is EROMED, ETROCIN, EYTHROCIN. The dosage of the medicine for adult is 250-500 mg for 6 hours ( max- 4g / day ) and for children 30-60 mg / kg / day. The side effect of the Erythromycin base is a remarkably safe medicine. Mild to severe epigastric pain is experienced by many patients, specially children, on oral therapy. Diarrhoea is occasional. At higher doses of the medicine may cause reversible hearing impairment. Allergic reactions, headache, taste disturbance, eosinophilia, reversible hearing loss, and hepatotoxicity are an infrequent occurrence with all the macrolides. Macrolides should be avoided in severe liver disease due to increased risk of hepatotoxicity and altered handling. Macrolide are contraindicated if there is a history of hypersensitivity.