MEDICINE FOR ANTI SPASMODIC
The medicine which is used to prevent or relief pain and spasm in irritable bowel syndrome especially of the smooth muscles and to reduce the movement of the intestine i.e., gut. It is also used in some other conditions such as diverticular disease. Gut is partially controlled by an extensive network of neurons. The neurons work by controlling smooth muscle which is present in the walls of the gut. This muscle which is responsible for gut movements. The neurons are stimulated by various different chemicals produced by our body. These chemicals work by binding to special receptors on the muscle surface, which causes either relaxation or contraction of the smooth muscle. Contractions of the smooth muscle cause food in the gut to be moved further along the gut. However, in conditions such as irritable bowel syndrome these contractions can occur too frequently or painful, causing some of the symptoms experienced. Antimuscarinics work by blocking muscarinic receptors. These are a class of receptors found in the gut which cause muscle contraction. Blocking the receptors reduces the amount of contractions and it should help to relieve some of the symptoms associated with irritable bowel syndrome.Smooth muscle relaxants work directly on the smooth muscle in the wall of the gut.
The commonly used medicine is Dicyclomine Hydrochloride. The brand name is MEFTAL SPAS, CYCLOPAM. The dosage of the medicine for adult is 160 mg per day in 4 equally divided doses. The medicine do not have any serious side effects. If side effects occur, they are usually minor. The most common side effects of the medicine are flatulence and bloating, heartburn, constipation, dry mouth. Dicyclomine Hydrochloride may produce drowsiness or blurred vision. The patient should be warned not to operating a motor vehicle or other machinery or to perform hazardous work while taking this medicine.
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